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PROFESSOR MIKKO LAMMI

I am Biochemist and Cell Biologist interested in connective tissue, particularly cartilage and bone. As a former lecturer of the topic, I am also excited in cell biology in general.

 

I have done my major research career in Kuopio, Finland, starting with my Master's thesis in 1985. In January 2015 I moved from the University of Eastern Finland to Umeå University. In September 2015 I also started as a part-time professor at Xi'an Jiaotong University in Xi'an, China

MOST RECENT PROJECTS

Cartilage Tissue Engineering
Stem Cell
Research
Kashin-Beck
Disease

SOME RECENT ARTICLES

Wang X, Ning Y, Poulet B, Huang R, Hu M, Li C, Zhou R, Lammi M, Guo X: Comparison of the major cell populations among osteoarthritis, Kashin-Beck disease and healthy chondrocytes by single-cell RNA-seq analysis. Cell Death Dis 12(6): 551, 2021 [Pubmed] [Full text]

Lei J, Amhare AF, Wang L, Lv Y, Deng H, Gao H, Guo X, Han J, Lammi MJ: Proteomic analysis of knee cartilage reveals potential signaling pathways in pathological mechanism of Kashin-Beck disease compared with osteoarthritis. Sci Rep 10(1): 6824, 2020 [Pubmed] [Full text]

Wang X, Jin Z, Chen M, Duan D, Lammi MJ, Guo X, Chang Y: Inhibiting the aberrant activation of Wnt/b-catenin signaling by selenium supplementation ameliorates deoxynivalenol-induced toxicity and catabolism in chondrocytes. J Cell Physiol 235(5): 4435-4442, 2020 [Pubmed] [Full text]

Ning Y, Wang X, Lammi MJ, Guo X: Changes in the NF-KB signaling pathway in juvenile and adult patients with Kashin-Beck disease. Exp Cell Res 379(2):140-149, 2019 [Pubmed] [Full text]

Prittinen J, Ylärinne J, Piltti J, Karhula S, Rieppo L, Ojanen P, Korhonen RK, Saarakkala S, Lammi MJ, Qu C: Effect of centrifugal force on the development of articular neocartilage with bovine primary chondrocytes. Cell Tissue Res 375: 629-639, 2019 [Pubmed] [Full text]

 

Li W, Hirvasniemi J, Guo X, Saarakkala S, Lammi MJ, Qu C: Comparison of bone texture between normal individuals and patients with Kashin-Beck disease from plain radiographs in knee. Sci Rep 8: 17510, 2018 [Pubmed] [Full text]

Lammi MJ, Piltti J, Prittinen, Qu C: Challenges in fabrication of tissue-engineered cartilage with correct cellular colonization and extracellular matrix assembly. Int J Mol Sci 19: E2700, 2018 [Pubmed] [Full text]

Lammi MJ, Qu C: Selenium-related transcriptional regulation of gene expression. Int J Mol Sci 19: E 2665, 2018 [Pubmed] [Full text]

Ning Y, Wang X, Zhang P, Anatoly SV, Prakash NT, Li C, Zhou R, Lammi M, Zhang F, Guo X: Imbalance of dietary nutrients and the associated differentially expressed genes and pathways may play important roles in juvenile Kashin-Beck disease. J Trace Elem Med Biol 50: 441-460, 2018 [Pubmed] [Full text]

 

Wang S, Yan R, Wang B, Du P, Tan W, Lammi MJ, Guo X: Prediction of co-expression genes and integrative analysis of gene microarray and proteomics profile of Keshan disease. Sci Rep 8: 231, 2018 [Pubmed] [Full text]

 

Wu C, Liu H, Zhang F, Shao W, Yang L, Ning Y, Wang S, Zhao G, Lee BJ, Lammi M, Guo X: Long noncoding RNA expression profile reveals lncRNAs signature associated with extracellular matrix degradation in kashin-beck disease. Sci Rep 7: 17553, 2017 [Pubmed] [Full text]

 

Piltti J, Bygdell J, Fernandez-Echevarria C, Marcellino D, Lammi MJ: Rho-kinase inhibitor Y-27632 and hypoxia synergistically enhance chondrocytic phenotype and modify S100 protein profiles in human chondrosarcoma cells. Sci Rep 7: 3708, 2017 [Pubmed] [Full text]

Last updated June 18, 2021

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